Wrinkle proof, repair & renew your skin with nature's gift for a lifetime of healthy, graceful skin

Discovery of Natural Skin Revitalizer & Master Antioxidant Serum, Validated by Science, Regenerates Skin & Improves Elasticity

Powerful antioxidant scavenges free radicals & prevents premature wrinkles

Repairs sun damaged skin & increases DNA repair at the cellular level

Triggers your body's own skin regeneration activators

Reactivates a youthful look & skin's radiance

Softens, tightens, firms and strengthens skin

Dissolves imperfections & reduces wrinkles

Complete & Balanced Natural Solution

Women today are more active and vibrant into their 40's 50's 60's 70's and beyond than ever before. Anti-aging self care is key to a healthy lifestlyle. Today over 60 million women in the United States are dealing with the many issues of growing older and maturing beauty.

Wrinkles and aging skin is part of it.
It happens to all of us.
And even though, at times, it might feel like there is no room for the more mature woman in today's fashion industry, we think differently. We think you are worth a skin treatment especially made for this purpose. Using science and nature's gifts your skin can be renewed and you can feel proud of it again. Here, is a treat for you.

Thanks to the discovery of a natural antioxidant and powerful skin regenerating complex we can counteract the deleterious effects of skin aging and the mayor culprits of the wrinkling process, turn back the effects of free radicals and do not settle for the reflection of sun damage.

BIO SKIN REVITALIZER address the three major ways in which a mature woman's skin changes: it gets thinner, sun damage accumulates and the protective barrier decreases.

Mother nature's wisdom at work for mature skin revitalizing

The topical application of BIO SKIN REVITALIZER which embodies a newly discovered natural skin regenerating serum, acting in synergy with Vitamin C, and other powerful natural ingredients can nowadays help us remain graceful.

The natural serum, according to scientific breakdown, is packed with traces of calcium, copper, zinc and proteins, complex polysacarides, enzymes, antioxidants and intercellular communication molecules that nurture & re-activate the beauty of more youthful days.

The molecular basis for the regenerative properties of the naturally ocurring serum have been validated by science. An it's revitalizing effects are endorsed by many of our customers, as you may read further below.

This skin regenerative serum is collected with our propietary biotechnology from a living creature that produces it to thrive protected from the effects of its exposure to sun radiation and pollution and to repair its own skin -which is similar to human skin- and even to restore functionality to some of its organs when damaged.

On human skin the serum activates the skin's regenerative ability and speeds skin turnover, thus replacing dead cells by fresh cells pushed to the skin's surface, making the outer epidermal layer smoother and naturally hydrated, thereby giving the skin a younger-looking appearance.

The serum is readily absorbed by the skin and stimulates skin turnover and skin regeneration without causing any trauma, unlike most anti-aging or anti-wrinkle physical (microdermabrasion) or chemical (Alpha or Beta Hydroxy and other acid) exfoliation creams.

BIO SKIN REVITALIZER is a 100% pure, natural skincare product that boosts skin cell proliferation, leading to a much necessary thickening of the skin. In turn, a thicker skin layer results in a smoother appearance of the surface of the skin.

Freckles and age spots start to fade away. Pigment cells (melanin) are more evenly distributed, helping to prevent the appearance of new age spots - even scars that you have lived with a long time will appear much softer and be much less noticeable. The skin becomes richer in glycosaminoglycans (GAG) which are the natural water holding molecules in the dermis and in collagen and elastin that promote resilience and firmness. All these effects make skin look younger and healthier.

In the skin BIO SKIN REVITALIZER

Increases cellular turnover of healthy keratinocytes (the cells that migrate from the basal layer and create the outer layer of protective cells), pushing fresh cells to the surface more quickly and promoting old cells to slough off faster

Increases calcium fixation by keratinocytes and thereby reinforces cell cohesion and improves the communication between keratinocytes

Stimulates fibroblasts proliferation and activates scenescent fibroblasts, the cells that give rise to collagen, elastin and the water holding molecules that retain moisture, resulting in stronger, more resilient skin

Increases GAG synthesis (water holding molecules, skin matrix components & intercellular messengers), providing natural hydration to the epidermis and dermis

Increases microcirculation and the formation of new healthy blood vessels, improving blood flow and oxygenation of the skin

Optimizes the skin's metabolism, the skin is more resistant and perfectly acts as a protection barrier against external aggressions

Acts as an oxidative-defense complex, scavenging free radicals and as an anti-inflammatory and immune modulating resource that boosts the immune system and enhaces the ability of the skin to withstand stress from UV solar radiation, pollution and wear and tear.

What is the beauty secret that makes all this possible?

You've probably never heard anything like this! It's been before our eyes in orchards and our backyards and it may lead you to a lifetime of healthy skin.

BIO SKIN REVITALIZER embodies the ONLY substance found in NATURE created by a little creature endowed with the ability to cope with (a) daily exposure to trillions of free radicals from a variety of sources: the sun's ultraviolet rays, pollution, harsh dry weather conditions, and external stress while it thrives exposed nude to the sun rays and the hazards of the environment, pretty much like we merry around exposing our nude face and other parts of our skin; (b) keep its skin permanently moisturized, and; (c) regenerate its skin and even some organs when damaged.

To moisturize, protect, repair and achieve healthier cell regeneration this little creature produces a fluid that it copiously bathes onto its skin. Scientific breakdown has characterized the fluid as a complex compound of glyco or sugar chain molecules bound to proteins, peptides, enzymes, co-enzymes and oligoelements with strong biological activity.

The same molecules are present in human skin when skin is injured, specially in younger people, where skin wounds heal quickly and without aberrant scarring, but are scarce or in inadequate proportion in adults.

We collect this fluid from live creatures of the Phylum mollusca, class gastropoda, species Helix Aspersa Müller, also known as the humble brown garden snail. Using proprietary biotechnology and a labor-extensive process, no harm is inflicted upon the snails while we gather their precious gift.

It is this same substance that helps to protect the snail's body from oxygen radicals when it comes out of his shell after hibernating; from the effects of ultraviolet solar radiation; and from opportunistic micro-organisms always ready to intrude when moist skin is injured.

Also, what is far more interesting to us humans, it is the exact same fluid used by these little creatures, that happen to have a skin made of the same structural elements of human skin: —collagen, elastin, water holding molecules, etc.— to protect & repair their skin, organs and shell whenever they are damaged.

What Recent Science Says and Why Our Customers Rave?

Link: Skin Regeneration Properties of Mollusk Secretion Copyright © 2007 S. Karger AG, Basel

In this scientific report, some of the cellular and molecular effects underlying the observation that the snail secretions have regenerative effects on human skin are outlined. First, the secretion has enzyme antioxidant SOD (Superoxide Dismutase) and GST (Glutathione - often called the “master antioxidant") activities, as well as multiple modes of antioxidant action, acting at the level of free radical production and also sequestering free radicals. In addition, it stimulates fibroblast proliferation and rearrangement of the actin cytoskeleton of cells.

Additional mechanisms involved in the regenerative effect of the secretion include the stimulation of extracellular matrix assembly and the action of regulatory proteins known as Tissue Inhibitors of Metalloproteinases (TIMPs) responsible for the reversible inhibition of metalloproteinase (MMP) enzymatic activities, responsible for maintaining a balance between the degrading of damaged tissues and their new synthesis. This also limits the extent of the damage during wounding and scar formation and attenuates the signs of aging by reducing the degenerative effects of what usually becomes excessive MMP enzymatic activity.

Together, these effects provide an array of molecular mechanisms underlying the secretion's induced cellular regeneration and supports its use in regenerative therapy at the cellular level.

Clinical Trials

Two studies that provide clinical evidence of the positive effects of the snail serum on human skin are summarized below: one is on the effects of the snail serum on people affected by photo-aging (aging due to accumulated damage from exposure to solar radiation) and the other can be read by following the blue link with the words radio dermatitis at the end of this paragraph and is about the positive effects on skin of patients diagnosed with breast carcinoma and about to initiate or undergoing radiotherapy treatment which otherwise suffer from blisters, dryness, severe cracking of their skin due to their exposure to ionizing radiation from radioactive materials used to destroy cancer cells. Link: radio dermatitis

Evaluation of the Anti-Wrinkle and Reaffirming Efficacy of a Cryptomphalus Aspersa-based Product (CAS) in the Treatment of Skin Photoaging M.J. Tribó, E. Serra-Baldrich, M. Asin, J.A. Camarasa. Dermatología & Cosmética, March (vol IX), 1999.

Ultraviolet light as well as frequent contact with harmful environmental chemicals such as ozone leads to the formation of excessive quantities of reactive oxygen species on the skin. Free reactive oxygen radicals cause destruction of biomembranes by oxidizing unsaturated fatty acids and protein oxidation in human as well as depolarization and crosslinking of biopolymers. This induces a spectrum of well documented acute responses such as erythema, hyperproliferation, desquamation and with chronic irritation a general degradation of collagen together with an accumulation of abnormal elastin deposits in the dermis resulting in premature skin aging.

The skin's own defense system is mainly based on the functionality of superoxide dismutase (SOD). Endogenic SOD is found at high levels in the stratum corneum but only low baseline levels are found in the dermis of people with photoaged skin. Also a significant depletion of antioxidants enzyme expression is observed within the strateum corneum and in their epidermis. The endogenous level of SOD decreases significantly. A replacement by using cosmetic formulations is therefore necessary. Externally applied SOD is able to penetrate into the intact stratum corneum and reach the upper layers of the epidermis, as has been shown using a fluorescent dye (FITC) labeled enzyme.

The report confirms a protective effect of the snail secretions in topical application against UV induced cutaneous damage and to overcome a lack of endogenic SOD necessary to restore the antioxidative homeostasis of the skin.

The study focused on five characteristics of skin aging due to excessive sun exposure.

A cream formulated with the snail serum was applied to the face of 32 individuals who showed signs of facial photoaging for an eight-week period on a continuous basis. The subjects were evaluated at 2, 4 and 8 weeks of treatment using a clinical evaluation method and the results were correlated with those seen with the use of instrumental techniques. Subjects also kept a subjective journal of their own observations and feelings towards the product which were evaluated at the end of the study.

The results of the study were very positive, affirming the snail serum as a true treatment in the fight against photoaging. Both according to the measurements taken by the instruments and image analysis programs, wrinkle depth is substantially aided by the product. Hydration is significantly improved due to the moisture retaining ability the serum imparts to skin.

Not only were the results processed by the instruments used to measure them positive, the subjects all had positive visual results, according to their journal entries. All study participants were happy with the topical treatment of photoaging in the study. Firmness, elasticity, and all the other side effects of excessive sun exposure were improved using the product with snail serum as a topical agent. Users' subjective comments indicate considerable comfort and satisfaction with the results of the experience.

Comments: the study was done in 1999 with the snail serum as part of a base cream that is different than the ingredients and technology we use in BIOCUTIS products which allows for a more deeper penetration of the serum into the skin and its proper release within the target cells.

The clinical efficacy of a cosmetic product is rarely confirmed by histological and immunohistochemical analyses. Our in-vivo studies with 15 women aged 35-65 of Fitzpatrick skin types II and III confirm that treatment with the snail serum leads to significant subjective (clinical signs and satisfaction) and objective (profilometry) improvements in cutaneous photoaging, confirmed by the improvement of subjects histopathological condition.

Skin Renewal & Regeneration

The skin is a continuously self-renewing organ, with a complex, multilayered kinetic organization. The epidermis contains mainly keratinocytes, along with a minor population of dendritic cells, stem cells, and possibly a pool of quiescent cells (a dormant reservoir).

Tissue stem cells are responsible for replenishing and maintaining a population of cells which make up a functioning organ. They divide by asymmetric cell division where one daughter remains a stem cell while the other daughter becomes a transit cell, which divides a defined number of times and differentiates. A fully differentiated cell has a finite life-span. A tissue can be maintained by various strategies. Stem cells can divide often and differentiated cells die often (fast turnover). Alternatively, stem cells can divide infrequently, and the differentiated cells are long lived (slow turnover).

Genetic alterations and mutations can interfere with tissue homoeostasis. Mutations can induce senescence and apoptosis, and this can result in a reduction of the number of functioning tissue cells which could correlate with tissue aging. Alternatively, mutations can result in the carcinogenic transformation of cells and the formation of a tumour.

As the first line of living cells of the epidermis, keratinocytes are the first target hit by the UV range of sun radiation.

Keratinocytes originate in the basal layer of the epidermis, through division of a population of stem cells. The daughter cells then divide several times as transit amplifying cells, which lose proliferative capacity and differentiate into post-mitotic, keratin-rich cells as they migrate upward to the spinous layer of the epidermis. As these cells continue their transit through the granular layer, they become anucleate and form the uppermost, cornified layers which ultimately are sloughed off. Turnover of the epidermis allows the organ to maintain its barrier function, repair injured skin in wound healing, and respond to stimuli that promote or inhibit cell proliferation.

Fortunately, you can turn back the clock on your skin

Even if you did not properly care for your skin in years past, BIO SKIN REVITALIZER can help repair sun damage and reverse some of the effects of both biological and mechanical aging. Because youthful, healthy skin portrays confidence and beauty, we are all concerned with what we assume is inevitable skin aging. The good news is that we have more control than we realize over the rate at which our skin ages. Maintaining youthful skin starts with good skin care.

Over the years, and specifically between the ages of 25-30, the cell renewal process slows down. This means our skin starts to look dull, with an uneven thickened texture. In some cases, our complexion can look uneven, because dead skin cells build up on the surface. However, even before the age of 30 our skin needs exfoliating action: a metropolitan lifestyle and contact with pollutant particles can negatively affect cell turnover.

Air pollution not only threatens our health but also our looks!

Every day, air pollution attacks plants and buidings – and for sure, our skin. The presence of oxides, hydrocarbons and particles of heavy metal, particularly iron, blocks normal epidermal respiration, damaging the skin's natural protective film and promoting the production of free radicals, which accelerate cell aging.

This is why the number of people who suffer from hypersensitivity and allergies - even at a young age - continues to rise.

Delicate, vulnerable skin with a tendency to redden easily; problems with fragile capillaries, irritability or even allergies. Dry, dehydrated skin, in some cases with a tendency towards oiliness.

These are the characteristics of hypersensitive skin, and dermatologists have noted a constant increase of people with this kind of skin.

This is why BIO SKIN REVITALIZER is necessary not only for mature skin, but also for younger skin. It purifies the skin by getting rid of harmful substances. It also improves the flow of oxygen to skin cells and stimulates cell metabolism, neutralizing the corrosive effect of pollutants, stimulating cell respiration and slowing down the skin's aging process, which also yields an anti wrinkle effect.

Remember, a healthy lifestyle, a positive attitude and proper skin care can keep you looking and feeling younger and beautiful in your 40's, 50's, 60's and beyond.

Here are three tips to enhance natural skin care as you grow older:

1. If you smoke, stop. Smoking has been shown to accelerate aging of skin, so quitting now is important for good skin health.
2. Eat a well-balanced diet -- with or without a multivitamin. A healthy diet helps the skin get the nutrition it needs to help repair ongoing damage from the sun and other environmental elements.
3. The only means to achieving near-perfect sun protection and defense against skin cancer and signs of skin deterioration including textural changes, irregularity in colouring and the collagen degradation that leads to wrinkling is to make daily use of both a proven, potent, stable antioxidant and a true broad spectrum sunscreen.

BIO SKIN REVITALIZER: One Month's Intense Treatment Serum

A deeply moisturizing, powerful antioxidant & skin regenerating intensive treatment serum for use at night before bedtime during 30 days on face, neck and ears. Follow with BIOSKINCARE during the day or follow with BIO SKIN REJUVENATION in the morning if you wish to regulate melanocyte production and reverse & prevent hyperpigmentation and promote the even distribution of melanin, to eliminate unwanted dark patches and age spots.

Ingredients: Helix Aspersa Müller Glycoconjugates, Seaweed Extracts, Hyaluronic Acid, Purified Water, Stay C 50 (stable form of Vitamin C), Suprapein (natural preservative made only with botanical extracts. Please note that the natural volatile elements in the preservative have a pleasant menthol fragrance and may make your eyes sting a little if you place the serum too close to your eyes, but such tingling sensation will go away soon).

Invigorates skin and triggers the repair & regeneration of damaged cells and the balanced & orchestrated assembly of new connective tissues, removing dull skin and skin imperfections and flaws, as well as all types of skin blemishes.

Directions: Apply your intense BIO SKIN REVITALIZER treatment with your fingertips in circular motion on all your face, ears and neck in the evening before bedtime during one month and apply BIOSKINCARE in the morning.

Reap the benefits of natural results your family and friends will notice – yet so natural they still will not be sure you really had “something done”.

Stop procastinating and click now to order and get your skin healthy and natural again rapidly!